Acoustofluidics papers Biomedical Engineering
List of publications
But hearing the words can still be scary. Here are 10 more facts about prostate cancer. Breast cancer is the second most common cancer found in women — after skin cancer — but that doesn’t mean men aren’t at risk as well. Although the percentage of cases in men is much lower than in women, male breast cancer accounts for a por Whether colon cancer runs in your family or you’re interested in learning about health conditions as part of an effort to improve your well-being, it’s important to understand this type of cancer. According to the American Cancer Society, a Lung cancer is a serious illness which none of us wish to face.
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The technology is currently finding increased applications in bioanalytical and clinical applications of cell handling and manipulation. The throat includes the esophagus, windpipe (trachea), voice box (larynx), tonsils and epiglottis. Throat cancer refers cancer that develops in your throat (pharynx) or voice box (larynx). Your throat is a muscular tube that begins behind your nose and ends in your neck.
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cancer cells and A498 renal carcinoma cells. In cell suspensions containing viable and dead cells, we added a density modifying molecule (iodixanol) at several concentrations ranging from 0% to 30% v/v and studied the mixed cell populations during acoustophoresis in a straight channel.
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The plasmapheresis platform is currently being integrated with cancer bio-marker microarrays for on-line multiplex immunoassaying, including secondary detector antibody incubation.
Sarcomas can either be bone or soft tissue, with additional sub-classifications depending on the origin of the cells (according to The Sarcoma Alliance). Sarcoma is rare and
The pancreas is an organ that releases enzymes involved with digestion, and hormones to regular blood sugar levels. The pancreas is located behind the stomach, so having pancreatic cancer doesn't involve a palpable mass that you can feel.
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Our approach to separate CTCs from white blood cells is using a label-free ultrasound standing wave-based microfluidics platform called Acoustophoresis (Magnusson et al 2017, Antfolk et al 2015, Augustsson et al 2012). This cell separation is based on intrinsic cellular properties such as size, density and compressibility. Augustsson, Per et al.
No significant immediate or long-term effects on proliferation could be detected in the DU145 prostate cancer cells subjected to acoustophoresis compared to the untreated cancer cells. Schematic representation of an acoustophoresis chip that is operated using frequency modulation for cancer cell enrichment.
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Materials and Methods Ethics Statement Label-free concentration of viable neurons, hESCs and cancer cells by means of acoustophoresis† Marina C. Zalis , a Juan F. Reyes , b Per Augustsson , c Staffan Holmqvist , d Laurent Roybon , d Thomas Laurell c and Tomas Deierborg * a Using this microchannel configuration, several publications have shown cancer cell lines (breast and prostate) being efficiently separated from WBCs from RBC-lysed blood using acoustophoresis with BASWs [3, 20].This label-free separation occurs because larger-sized cancer cells focus faster to the center pressure node than WBCs in the separation channel; thus, if flow rates are optimized the WBCs will flow through the side outlet channel and cancer cells will be enriched in the collected Figure 4: Percentage of viable cells after one passage through the acoustophoresis channel. CONCLUSION We believe that this work contributes principal proof of concept showing that acoustophoresis has potential for use in clinical diagnostics of CTCs in cancer patients. Moreover, the modular selection criteria allows for either high clearance Microfluidic, label-free enrichment of prostate cancer cells in blood based on acoustophoresis. Circulating tumor cells (CTC) are shed in peripheral blood at advanced metastatic stages of solid cancers. Surface-marker-based detection of CTC predicts recurrence and survival in colorectal, breast, and prostate cancer. acoustophoresis based separation reports a cancer cell recovery up to 87% (i.e.